The Medications for Opioid Use Disorder (MOUD) Playbook is a practical guide developed by AHRQ for providing MOUD and immediate care for patients with opioid use disorder (OUD) in primary care and other ambulatory care settings. It was most recently revised in February 2026.

This interactive, web-based product is reviewed quarterly and updated as necessary. It includes the latest guidance, tools, resources, tips, and examples that address key aspects of MOUD implementation. The Playbook will help you find your own path for implementation by applying knowledge about successful approaches and navigating possible barriers.

Medications for Opioid Use Disorder Playbook | The Academy